Biologicals
Innovative protein-based and
cellular therapeutics
Drug discovery
Novel therapeutics to
tackle incurable diseases
Herbal medicines
Innovative natural products
with specific health effects

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List of successful applications

R&D services

CRO services:

 

1. Protein cloning: Our research team undertakes the cloning, expressing and cleaning of proteins required for biological studies.


2. Development of drug delivery technologies and vectors on demand: the experience of our experts allows the planning, development, synthesis and labeling with flurescent tracers on demand to deliver biological macromolecules (proteins, nucleic acids, etc.) into cells.


3. Contract research: Conducting in vitro and in vivo preclinical tests from HIT validation to animal tests in neurodegenerative (Alzheimer’s, Parkinson’s disease, AMD), inflammation (sepsis, acute pancreatitis) and tumor models. The process includes:

a. Molecular modeling and in silico docking

b. QSAR structure activity studies

c. disease-specific testing focusing on target molecules (beta-amyloid, NFkB)

d. Measurement of in vitro toxicity and in vivo immunogenicity in reporter cell lines  (NFkB, AP1, HSP, etc.)

e. Disease-specific in vivo transgenic animal models (APPswe, 4T1, etc.)

f.  The experiment shall include the statistical analysis of the results


4. Bioinformatics and data mining: We offer gathering and organizing literature data about molecule groups, drug targets and candidates from scientific articles and patents into a user-friendly database. Moreover we take patent research and drawing up dossiers about preclinical drug development.


5.  Development and functional validation of nutraceuticals and disease-specific medical foods

 

For deteals please contac us: info@pharmacoidea.eu 

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