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Drug discovery

Located at the hometown of Nobel Laureate Albert Szent-Györgyi, the Pharmacoidea Ltd. is developing novel therapeutics for diseases with unmet medical needs. The Pharmacoidea Ltd. has disposal of state-of-the-art technologies that can validate efficacy of its innovative therapeutics in preclinicals models and also in the clinics. 

From bioinformatics to experimental cellular therapeutics against carcinomas, Pharmacoidea’s R&D portfolio covers a broad spectrum of drug discovery. Pharmacoidea employs system biology approach to identify the best target molecules (such as beta-amyloid in Alzheimer’s disease) to tackle the disease of interest. Pharmacoidea’s discovery platform integrates in vitro, ex vivo and in vivo bioassays to identify and validate molecular targets of specific diseases. Compounds effective on in vitro targets are continuously being studied in transgenic animals, genetically modified to produce the pertinent protein validated as target in the particular disease. Experimental cellular therapeutics are also being developed to find a the cure for metastatic carcinomas. 

Wet-lab science is carried out at Pharmacoidea’s laboratory rented at the Biological Research Center (BRC) of the Hungarian Academy of Sciences (www.brc.hu), a Centre of Excellence of the EU. The BRC has a broad selection of drug discovery technologies, central laboratories for bioinformatics, nucleic acid sequencing and synthesis, protein sequencing (MALDI TOF), cell sorting (FACS) and DNA chip analysis, confocal laser- and electron microscopy and imaging, as well as many specialized instruments for the disposal of Pharmacoidea’s researchers. In this highly motivating and ideal scientific atmosphere, the Pharmacoidea’s team has been carrying out both nationally and EU-funded R&D projects in the field of drug discovery and experimental therapeutics. 

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